What Will Happen After Mixing Cialis (Tadalafil) and Viagra (Sildenafil)?

What Will Happen After Mixing Cialis (Tadalafil) and Viagra (Sildenafil)?

Viagra and Cialis are the world’s most popular medications prescribed for the treatment of acute or chronic erectile dysfunction. These branded meds are based on the active substances – Sildenafil and Tadalafil – that belong to the same class of PDE5 inhibitors. Since these medications are in the same drug family, they act approximately in the same way: after using, they cause the dilation of the vessels of a penis. Basically, both drugs just pump enough blood to a penis to make it harder when a man is aroused.

Mixing Cialis (Tadalafil) and Viagra (Sildenafil)

My Canadian Pharmacy believe that combining Viagra and Cialis or generic ED pills based on the same active components is a bad idea. However, some medics recommend using both drugs, though at different time.

What does it mean? You may take Viagra and then Cialis pills or vice versa but within a 24-hour interval. Suppose, you have a date, you take one Cialis pill, then enjoy an intimate evening. However, if Cialis doesn’t act like expected, it is allowed to take one Viagra pill, but in 24 hours or even later since the action of Tadalafil usually lasts up 48 hours.

There are other differences when it comes to the use of these similar yet not alike medications for ED treatment. Let’s take a closer look at differences and similarities of Viagra and Cialis. Mixing these drugs is a wrong idea but it may happen if to stay cautious.

How does Viagra act?

After taking a Viagra pill, Sildenafil causes the relaxation of smooth muscles in the cavernous body of a penis. Naturally, blood flow increases. Then the process of inhibition of the enzyme phosphodiesterase 5 begins. In simple terms, the penile blood vessels expand, blood flow increases, and this contributes to the onset of erection.

How does Cialis act?

Tadalafil effect is somewhat different from Sildenafil. Cialis acts temporarily and after the drug is removed from a male body, its action is terminated. Tadalafil acts selectively. The main effect is that it has no effect on phosphodiesterase of other types, but affects only the 5th type of PDE inhibitors. During sexual arousal, nitric oxide is released, and Cialis inhibits PDE5. Blood pressure in a penis increases, the smooth muscles of arteries relax. Naturally and painlessly erection occurs.

Both pills won’t work without arousal.

Viagra and Cialis: differences with the dosage administration

The dosage of these 2 meds is different. Viagra pills are available in 25, 50 and 100mg strengths. And Cialis doses are 2.5, 5, 10, 20 mg. The single doses of both drugs are selected individually.

After taking Viagra, the effect occurs in 30-60 minutes. Cialis can be taken 15-30 minutes before sexual intercourse. The action of Viagra is limited to 5 hours, and Cialis works up to 36-48 hours.

Cialis is typically prescribed for most males who have problems with maintaining erection and/or can’t prevent premature ejaculation. The recommended starting dose of Cialis is 10 mg that has to be taken before an intimate date.

Depending on the individual medical conditions, the prescribed dose can be increased to 20 mg or lowered to 5 mg, for a single dose. Commonly Tadalafil causes an erection that can last up to 36 hours. People who are taking medications should prevent themselves from taking a dose increased even by 10 mg in the next 72 hours after using the initial dose of 20mg. If to compare Cialis vs. Viagra, Cialis can be taken despite the food intake – it means food does not affect the drug’s absorption in the intestines.

Viagra is recommended for most patients who suffer from ED. It is required 50 mg of Viagra per dose with a 24-hour interval between doses. It should be taken about 1 hour before sexual intercourse. However, many doctors recommend taking Viagra anywhere between 4 hours to 30 min before a date. Based on efficacy profile and individual tolerability, the pill’s dose can be increased to 100 mg or lowered to 25 mg, for a single dose.

Common features of Viagra and Cialis pills that should be taken into account

Viagra or Cialis have very common precautions. People can’t intake both pills more than once a day. It is undesirable to drink alcohol while taking Sildenafil or Tadalafil. Side effects, by the way, are also similar. Due to the fact, the main effect is provided to the penile vessels. It is also strongly recommended to take pills with special care by those patients who previously suffered from any serious cardiovascular diseases.

Cialis and Viagra are both pharmaceutical drugs prescribed for the use by males who have erectile problems. That is the main reason to use these meds. No matter, what pill you prefer – Cialis or Viagra, you may still expect a bunch of health benefits:

  • Rapid onset of strong erections;
  • The possibility of repeated orgasms within the period of the pill’s time of action;
  • Long and bright orgasms should be expected as well;

Instead of summing up, it is worth saying that mixing Cialis (Tadalafil) and Viagra (Sildenafil) pills is a bad idea because the simultaneous use may lead to negative consequences to health. Be careful, follow the doctor’s instructions and enjoy a normal intimate life.


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