Dapoxetine – the active ingredient in Priligy
Dapoxetine is the first approved drug for premature ejaculation. On average, dapoxetine makes 2 to 3 times so far for the many Danes who experience this disorder. There is not a particular population that suffers from this condition. It affects more parts of the population, but fortunately there is an effective treatment for the suffering. Dapoxetine is the active substance in the product Priligy. It is usually prescribed for men between 18 and 64 years of age against premature ejaculation. The active ingredient has been on the market since 2009 and in this long period since launch, no similar substance has been approved.
Dapoxetine (chemical name: (+) – N, N-dimethyl-1-phenyl-3- (1-naphthyloxy) propylamine) belongs to a group of selective serotonin inhibitors (SSRIs) and ensures that serotonin production in the body is temporarily suppressed. Depending on the patient, it is possible to extend the time from penetration to ejaculation by 300%. The pill should only be taken once a day, approx. 1 to 3 hours before intercourse. Since dapoxetine is not a vital treatment, but a lifestyle, the cost of dapoxetine is not covered by the health insurance.
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What is premature ejaculation?
Premature ejaculation is also called premature ejaculation. This occurs most often in sexual dysfunctional men and, at one point or another, occurs between 20 and 40% of all men worldwide. A significant number of men believe that impotence and premature ejaculation are related, but there are both major differences – both physiologically and therapeutically. The medical treatment against sexual dysfunction in the form of premature ejaculation is dapoxetine, which is basically an antidepressant.
In the past, the cause of premature ejaculation was always found by a mental illness or physical impairment. However, recent studies have made up with the old, superficial diagnoses and have instead found the cause of the neurons.
Serotonin is considered to be the messenger among the neurotransmitters who decide when a man ejaculates. The so-called 5-HT2c receptors ensure postponement of men’s release. If there are not enough drugs to affect the receptors, you will not experience premature ejaculation. Another factor is that the 5-HT1A receptors stand to ensure the correlation between release and orgasm in men. However, this area may also be affected by unlearned protein to stimulate these receptors. If there is not enough drug to affect the receptors, it will be almost impossible to get an orgasm.
My Canadian Pharmacy tips on Priligy 30/60mg
Priligy should be taken shortly one hour before intercourse and the drug then has an effect for between 1-3 hours. Priligy is available in two different strengths of 30 mg and 60 mg, respectively. It is recommended that you start with the lowest dose to see how the medicine works on your body. For most men, a dose of 30 mg of Priligy is enough to have the desired effect on your body. Your dose can then always be increased if the lowest dose is not effective enough, and in that case you choose a higher dose the next time you shop at My Canadian Pharmacy.
As with any other prescription drug, you may potentially be affected by some side effects when taking your medicine. However, this can usually be avoided if you are careful about which dose you choose to buy. Of course, it is about finding the dose that best suits you and your body, which may be hard to know if you have not tried the medicine before.
The main rule, however, is that you should not buy the highest dose for the first time simply because of the potentially higher efficiency and success rate. Although the effect may be higher, the side effects will also be. There is no need to take the highest dose if a dose of 30 mg is enough to solve your early-challenge issues. So, the best thing you can do is start with the lowest dose and see how your body responds.
It is possible that you will experience the following side effects when taking Priligy: nausea, headache, diarrhea, dizziness. You can ask your doctor for side effects at Priligy before you buy it online. Our patient guidance is also available on phone and e-mail if you have questions about the product.
Please note that if you order Priligy for the first time through My Canadian Pharmacy, and this is the first time you need to take the medicine, you can only get a dose of 30mg. The dose can then be adjusted according to the effect as well as any side effects during your first treatment.
Chemical properties of dapoxetine (generic Priligy)
Dapoxetine is a white powder with a bitter taste. It is a Naphthyloxyphenylpropanamine derivative that is soluble in water. Dapoxetine is less resistant to the drug flouxetine. The short half-life of the drug means that it is only present in the body for one to two hours. This means that there is much less risk of side effects. Dapoxetine may be used against premature ejaculation in a man if:
- Ejaculation occurs within 2 minutes.
- Man has little control or poor control over one’s orgasms.
- Automatic ejaculation occurs at low sexual stimulation.
- Repeated failure to complete sexual intercourse is observed.
Early ejaculation is of course a subjective parameter, but experts have determined that ejaculation within 2 minutes after intercourse is premature.
Dapoxetine effects
Dapoxetine affects the serotonin in the body. Dapoxetine blocks the transport molecules that normally transport serotonin around the body. Dapoxetine therefore ensures that there is a lower concentration of serotonin in the brain, so that a larger amount of neurotransmitters continue to circulate in the body.
This means that you can maintain the excitement during intercourse for a long time. This increases the amount of unbound serotonin in the cerobrospinal fluid and therefore exposes the orgasm in men. That way, you will affect premature ejaculation on several parameters.
The inclusion of serotonin in the body is the main cause of men’s orgasm. When the body does not absorb serotonin, the orgasm will be exposed.
The effect of Dapoxetine varies between 60 and 180 minutes after ingestion of the pill. The pill therefore works quickly and this makes it ideal for treating premature ejaculation.
However, unlike other SSRIs, the duration will be much shorter because the drug is in the body for a relatively short period of time. The half-life is rapid, so effect time is affected, but on the other hand, the risk of side effects is also significantly reduced.
Dapoxetine clinical studies
Dapoxetine effect on premature ejaculation has been demonstrated in several international studies. Here it was investigated how effective the drug could expose semen during intercourse. These results confirm other studies from 2015 and 2014. Several studies confirm the effect of dapoxetine on a man’s performance anxiety that affects a man’s erection and release in general. Dapoxetine helps the man relax and reduce stress levels – especially during sex. The study also showed that men taking dapoxetine have much better control over their release.
Dapoxetine has been extensively tested during several studies. Side effects are often mild and temporary, and because the medicine is prescription, one should expect one whose risk of side effects.
However, we are all different, and therefore some will be able to take a high daily dose without side effects, while others will experience side effects at self doses. A 2011 medical examination tested 6,000 volunteers from 25 different straight and therefore you have a good overview of the risk of side effects. The most common side effects of dapoxetine are nausea, dry mouth, headache, diarrhea and insomnia.
Dapoxetine is an antidepressant and it is normal that antidepressants affect the desire for sex. However, a continuous study of the effect on the desire for sex in which Dapoxetine was compared with a placebo overdose. Here it turned out that dapoxetine had little effect on the desire for sex.
Important!
Information on this site is provided for educating purposes only. In patients with acute or persistent conditions, health-related tasks such as diagnosis and treatment should be carried out by a qualified healthcare worker. Please keep in mind that improper choice of medication and dosage can cause serious harm to your health. The owner of this site, as well as editors and authors are not responsible for any damage caused by the practical application of any information published here.